SCHEMBL1273

SCHEMBL1273

[c]1ccncc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17044828 1.00 TSHR (0.33)
SCHEMBL28358626 0.96
SCHEMBL27913386 0.96
SCHEMBL28797160 0.96
Hydrochloric Acid SCHEMBL3866953 0.96
SCHEMBL27588506 0.96
Bromide SCHEMBL8905110 0.96
SCHEMBL27678168 0.86
Pyrimidine SCHEMBL27874959 0.83 TSHR (0.39)
SCHEMBL6185048 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 125839 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410577-B1 None US claimed
US-20240239821-A1 N-ACYL FOSMIDOMYCIN PRODRUG ANALOGS AS NOVEL ANTIINFECTIVE AGENTS THE GEORGE WASHINGTON UNIVERSITY 2024-07-18 US claimed
EP-4399206-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES Redona Therapeutics, Inc. (US) 2024-07-17 EP claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118344340-A Quinolinone compound containing 1,2, 4-triazole or 1,3, 4-oxadiazole structure and preparation and application thereof 贵州大学 2024-07-16 CN claimed
CN-118344342-A Substituted polyaromatic ring derivatives, compositions and uses thereof 康迈迪森(北京)医药科技有限公司 2024-07-16 CN claimed
US-12036291-B2 Probes for imaging huntingtin protein CHDI FOUNDATION, INC. (US) 2024-07-16 US claimed
CN-118324804-A Aromatic phosphonate compound and synthesis method thereof 海南大学 2024-07-12 CN claimed
WO-2024147125-A1 CYCLOBUTYL-SUBSTITUTED PHENOXY-DIOXETANES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-07-11 WO claimed
US-20240217968-A1 PHARMACEUTICAL COMPOUND Duke Street Bio Limited (GB) 2024-07-04 US claimed
US-3974275-A 1,4-Dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US claimed
US-3973024-A Analgesic and anti-inflammatory anilino-phenylacetic acid-(2,3 or 4 pyridyl)-methyl esters and derivatives CIBA-GEIGY CORPORATION (US) 1976-08-03 US claimed
US-3966749-A Novel synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols, the pharmaceutically acceptable acid addition salts thereof and intermediate useful in the preparation thereof INTERX RESEARCH CORPORATION (US) 1976-06-29 US claimed
US-3963731-A TREATMENT OF GOUT AND HYPERURICEMIA MERCK & CO., INC. (US) 1976-06-15 US claimed
US-3956343-A ANTIINFLAMMATORY AGENT AMERICAN CYANAMID COMPANY (US) 1976-05-11 US claimed
US-3951952-A 6-(ALPHA-(AMIDINO-AND IMIDOYLAMINOALKANOYLAMINO)ARACYLAMINO)-PENICILLANIC ACIDS PFIZER INC. (US) 1976-04-20 US claimed
US-3947577-A 1,2,4-TRIAZOLES MERCK & CO., INC. (US) 1976-03-30 US claimed
US-3941881-A Novel 3 or 5-aminopyrazolium salts and fungicidal use thereof AMERICAN CYANAMID COMPANY (US) 1976-03-02 US claimed
US-3935209-A 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity SYNTEX (U.S.A.) INC. (US) 1976-01-27 US claimed
US-3932301-A NYLON, POLYESTERS STERLING DRUG INC. (US) 1976-01-13 US claimed