SCHEMBL1273236

SCHEMBL1273236

O=C1C=CNC(=O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28574253 0.97
SCHEMBL5029860 0.76
SCHEMBL11315691 0.76
SCHEMBL7085702 0.74
SCHEMBL9640767 0.72 KMT2A (0.35)
SCHEMBL9641604 0.72 GAA (0.37)
SCHEMBL7548528 0.70 GSK3A (0.38)
SCHEMBL9525768 0.66 AHR (0.48)
SCHEMBL31663444 0.65 GAA (0.32)
SCHEMBL31663445 0.65 GAA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118516151-A Multipurpose oxypyridones and their functional use 英菲诺姆国际有限公司 2024-08-20 CN claimed
CN-118516152-A Multipurpose oxypyridones and their functional use 英菲诺姆国际有限公司 2024-08-20 CN claimed
CN-118516153-A Multipurpose oxypyridones and their functional use 英菲诺姆国际有限公司 2024-08-20 CN claimed
CN-118516154-A Multipurpose oxypyridones and their functional use 英菲诺姆国际有限公司 2024-08-20 CN claimed
CN-115746711-B Aluminum alloy mirror polishing solution and polishing method 东莞领航电子新材料有限公司 2023-07-14 CN claimed
US-8741897-B2 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 2014-06-03 US claimed
EP-2350007-A1 HETEROCYCLIC ANTIVIRAL ARYLPYRIDONE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2011-08-03 EP claimed
WO-2010049331-A1 HETEROCYCLIC ANTIVIRAL ARYLPYRIDONE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2010-05-06 WO claimed
US-20060084576-A1 2-(Chloro),4-(ethoxycarbonyl-isoprop-2,2-ylene-isoprop-2,2-ylene-oxycarbonyl-methyl),5-(methyl-thiazole; bactericides; herbicides; insecticides; fungicides; nematocides; algicides; molluscicides; construction materials; wood; clay; alkali resistance FISCHER REINER 2006-04-20 US claimed
EP-1349854-B1 HETARYL SUBSTITUTED HOMOTETRAMIC AND HOMOTETRONIC ACIDS AND THE USE THEREOF AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2006-04-12 EP claimed
US-20040097558-A1 Hetaryl substituted homotetramic and homtetronic acids and the use thereof as pesticides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-05-20 US claimed
EP-1366024-A2 SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES Esperion Therapeutics Inc. (US) 2003-12-03 EP claimed
EP-1363879-A2 SULFIDE AND DISULFIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES Esperion Therapeutics Inc. (US) 2003-11-26 EP claimed
EP-1351916-A2 ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES Esperion Therapeutics Inc. (US) 2003-10-15 EP claimed
CN-1412181-A Carboxylic acid derivatives inhibiting the binding of integrins to their receptors TEXAS BIOTECHNOLOGIES CORP (US) 2003-04-23 CN claimed
WO-2002030882-A9 SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS INC (US) 2003-02-20 WO claimed
US-20030022865-A1 Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses ESPERION THERAPEUTICS, INC. 2003-01-30 US claimed
WO-2002030884-A2 SULFIDE AND DISULFIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2002-04-18 WO claimed
WO-2002030863-A2 ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2002-04-18 WO claimed
WO-2002030882-A2 SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2002-04-18 WO claimed