Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.57 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273546 | 1.00 | NR1H2 (0.57) | NR1H2NR1H3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12215951 | 0.86 | NR1H2 (0.59) | NR1H2NR1H3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8219203 | 0.86 | NR1H2 (0.59) | NR1H2NR1H3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12789591 | 0.86 | NR1H2 (0.59) | NR1H2NR1H3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1164437 | 0.85 | NR1H2 (0.45) | NR1H2NR1H3SMN1; SMN2ABCB1CASP3 | |
| SCHEMBL1274127 | 0.84 | NR1H2 (0.54) | NR1H2NR1H3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23975518 | 0.84 | NR1H2 (0.58) | NR1H2NR1H3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1273147 | 0.83 | NR1H2 (0.40) | NR1H2NR1H3UCHL1USP30 | |
| SCHEMBL1273394 | 0.83 | NR1H2 (0.40) | NR1H2NR1H3UCHL1USP30 | |
| SCHEMBL1273270 | 0.83 | NR1H2 (0.40) | NR1H2NR1H3UCHL1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | BIRC5, XIAP, BIRC2 | NR1H2 4004/4885NR1H3 4178/4885SMN1; SMN2 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.