⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269968 | 0.82 | — | — | |
| SCHEMBL14938555 | 0.80 | — | — | |
| SCHEMBL9514161 | 0.79 | — | — | |
| SCHEMBL27629711 | 0.79 | — | — | |
| SCHEMBL51804 | 0.78 | — | — | |
| SCHEMBL1715624 | 0.78 | — | — | |
| SCHEMBL5504615 | 0.77 | — | — | |
| SCHEMBL270674 | 0.75 | — | — | |
| SCHEMBL9864400 | 0.75 | — | — | |
| SCHEMBL4923394 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062815-A | VMAT2 inhibitors and methods of use | 纽罗克里生物科学有限公司 | 2023-11-14 | — | — | CN | claimed |
| EP-4168409-A1 | VMAT2 INHIBITORS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2023-04-26 | — | — | EP | claimed |
| US-20110056887-A1 | REMOVAL OF OXO ANIONS FROM WATER | LANXESS DEUTSCHLAND GMBH (DE) | 2011-03-10 | — | — | US | claimed |
| EP-2292561-A2 | Removal of oxo anions from silicate-containing water | LANXESS Deutschland GmbH (DE) | 2011-03-09 | — | — | EP | claimed |
| US-20090069336-A1 | PYRIMIDOTHIOPHENE COMPOUNDS | Dymock, Brian William (GB) | 2009-03-12 | — | — | US | claimed |
| EP-1773842-A1 | PYRIMIDOTHIOPHENE COMPOUNDS | Vernalis (Cambridge) Limited (GB) | 2007-04-18 | — | — | EP | claimed |
| WO-2006008503-A1 | PYRIMIDOTHIOPHENE COMPOUNDS | VERNALIS (CAMBRIDGE) LTD (GB) | 2006-01-26 | — | — | WO | claimed |
| CN-1438278-A | Dye composition containing diamino-pyrazole type oxidation substrate and coupling agent | OREAL (FR) | 2003-08-27 | — | — | CN | claimed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | claimed |
| US-5047432-A | Antidepressants | THE BOOTS COMPANY PLC (GB) | 1991-09-10 | — | — | US | claimed |
| CN-1012733-B | Process for the preparation of therapeutic agents | BOOTS CO PLC (GB) | 1991-06-05 | — | — | CN | claimed |
| EP-0191542-B1 | ARYLCYCLOBUTYLALKYL AMINES AND THEIR USE AS ANTIDEPRESSIVE MEDICINES | The Boots Company PLC (GB) | 1988-06-08 | — | — | EP | claimed |
| CN-86100954-A | The preparation method of therapeutical agent and application | — | 1986-09-03 | — | — | CN | claimed |
| EP-0191542-A1 | Arylcyclobutylalkyl amines and their use as antidepressive medicines | The Boots Company PLC (GB) | 1986-08-20 | — | — | EP | claimed |
| EP-4330226-A1 | A DIISOCYANATE STABILIZER, USE THEREOF, AND DIISOCYANATE COMPOSITION | BASF SE (DE) | 2024-03-06 | — | — | EP | disclosed |
| US-20240010647-A1 | SUBSTITUTED PYRIDO[2,1-a]ISOQUINOLINES AS VMAT2 INHIBITORS | NEUROCRINE BIOSCIENCES, INC. | 2024-01-11 | — | — | US | disclosed |
| CN-117062815-A | VMAT2 inhibitors and methods of use | 纽罗克里生物科学有限公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-0191542-A1 | Arylcyclobutylalkyl amines and their use as antidepressive medicines | The Boots Company PLC (GB) | 1986-08-20 | — | — | EP | disclosed |
| US-4243418-A | Compositions for fireproofing polyester fiber materials with substituted sulphurylamides | CIBA-GEIGY CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4128687-A | Process for fireproofing polyester fiber materials with substituted sulphurylamides | CIBA-GEIGY CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |