Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.69 |
| ▸ | CA1 | P00915 | 11/20 | 0.69 |
| ▸ | CA2 | P00918 | 11/20 | 0.69 |
| ▸ | CA9 | Q16790 | 11/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6372736 | 0.85 | CA12 (0.79) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL12807414 | 0.83 | CA12 (0.75) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL9412855 | 0.83 | CA12 (0.75) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL31578430 | 0.82 | CA12 (0.74) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL14308477 | 0.81 | CA12 (0.72) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL9412854 | 0.80 | CA12 (0.73) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL13557760 | 0.78 | CA12 (0.65) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL21011843 | 0.78 | CA12 (0.65) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL21011827 | 0.78 | CA12 (0.65) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL19257250 | 0.78 | CA12 (0.65) | CA12CA1CA2CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932213-B2 | Solid phase synthesis with benzylidene linker attaching compound on glass slide; microarrays; drug screening | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-04-26 | — | — | US | disclosed |