Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 17/20 | 0.53 |
| ▸ | XIAP | P98170 | 11/20 | 0.53 |
| ▸ | BIRC3 | Q13489 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273664 | 0.88 | BIRC2 (0.52) | BIRC2XIAPBIRC3 | |
| SCHEMBL1273489 | 0.87 | XIAP (0.47) | BIRC2XIAPBIRC3 | |
| SCHEMBL1273662 | 0.86 | BIRC2 (0.54) | BIRC2XIAPBIRC3 | |
| SCHEMBL12900683 | 0.86 | BIRC2 (0.69) | BIRC2XIAPBIRC3 | |
| Hydrochloric Acid SCHEMBL1272894 | 0.85 | BIRC2 (0.71) | BIRC2XIAPBIRC3 | |
| SCHEMBL1272393 | 0.85 | XIAP (0.74) | BIRC2XIAPBIRC3 | |
| SCHEMBL1273012 | 0.85 | XIAP (0.74) | BIRC2XIAPBIRC3 | |
| SCHEMBL1273328 | 0.83 | BIRC2 (0.46) | BIRC2XIAPBIRC3 | |
| SCHEMBL1272403 | 0.81 | XIAP (0.54) | BIRC2XIAPBIRC3 | |
| SCHEMBL1273432 | 0.75 | XIAP (0.53) | BIRC2XIAPBIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | BIRC5, XIAP, BIRC2 | BIRC2 3/4885XIAP 2/4885BIRC3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.