Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846378 | 0.92 | ATM (0.55) | ATMTSHRHPGDHCAR2MAPT | |
| SCHEMBL1244640 | 0.92 | ATM (0.55) | ATMTSHRHPGDHCAR2MAPT | |
| SCHEMBL3296923 | 0.92 | ATM (0.55) | ATMTSHRHPGDHCAR2MAPT | |
| SCHEMBL3604815 | 0.92 | ATM (0.55) | ATMTSHRHPGDHCAR2MAPT | |
| SCHEMBL1244643 | 0.92 | ATM (0.55) | ATMTSHRHPGDHCAR2MAPT | |
| SCHEMBL27365356 | 0.90 | ATM (0.53) | ATMTSHRHPGDHCAR2MAPT | |
| SCHEMBL28167344 | 0.89 | HCAR2 (0.51) | ATMTSHRHPGDHCAR2NPSR1 | |
| SCHEMBL1274403 | 0.87 | HCAR2 (0.41) | ATMTSHRHPGDHCAR2ACHE | |
| SCHEMBL7770019 | 0.87 | HCAR2 (0.41) | ATMTSHRHPGDHCAR2ACHE | |
| SCHEMBL1274405 | 0.87 | HCAR2 (0.41) | ATMTSHRHPGDHCAR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046332-A1 | HYDROGEL BASED ON COPOLYMERS CONTAINING SILICONE | EVONIK ROEHM GMBH (DE) | 2011-02-24 | — | — | US | disclosed |