⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125682 | 0.77 | — | — | |
| SCHEMBL491235 | 0.74 | — | — | |
| SCHEMBL130601 | 0.72 | — | — | |
| SCHEMBL131167 | 0.72 | — | — | |
| SCHEMBL160033 | 0.72 | — | — | |
| SCHEMBL1734717 | 0.72 | — | — | |
| SCHEMBL18290946 | 0.72 | GRIK1 (0.39) | — | |
| SCHEMBL6656799 | 0.72 | GRIK1 (0.39) | — | |
| SCHEMBL13567329 | 0.72 | GRIK1 (0.39) | — | |
| SCHEMBL15080406 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107550860-A | A kind of acetylisovaleryl tylosin nano-emulsion and preparation method thereof | 成都泠汐尚品科技有限公司 | 2018-01-09 | — | — | CN | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20100204282-A1 | Reverse indoles as 5-lipoxygenase-activating protein (FLAP) inhibitors | AMIRA PHARMACEUTICALS, INC. | 2010-08-12 | — | — | US | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |