SCHEMBL1275751

SCHEMBL1275751

COC(=O)C(C)SCc1cc(CSC(C)C(=O)OC)c(O)c(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.42
HMGCR P04035 2/20 0.39
GAA P10253 6/20 0.38
VCAM1 P19320 1/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 4/20 0.35
CYP1A2 P05177 3/20 0.35
TSHR P16473 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP2D6 P10635 2/20 0.35
MEN1 O00255 2/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 2/20 0.35
BLM P54132 2/20 0.35
ATM Q13315 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 2/20 0.35
GSR P00390 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275454 0.89 HSPA5 (0.40) HSPA5HMGCRGAAVCAM1KMT2A
SCHEMBL5872981 0.86 HSPA5 (0.44) HSPA5HMGCRGAAKMT2AALDH1A1
SCHEMBL1275797 0.86 HSPA5 (0.44) HSPA5HMGCRGAAKMT2AALDH1A1
Dimethylamine SCHEMBL1275508 0.86 HSPA5 (0.44) HSPA5HMGCRGAAKMT2AALDH1A1
SCHEMBL1275832 0.85 EPHX1 (0.47) HSPA5HMGCRGAAKMT2AALDH1A1
SCHEMBL1274824 0.82 HSPA5 (0.50) HSPA5HMGCRGAAKMT2AALDH1A1
SCHEMBL1275507 0.79 HSPA5 (0.38) HSPA5HMGCRGAAKMT2AALDH1A1
SCHEMBL5873003 0.79 HSPA5 (0.42) HSPA5HMGCRGAAVCAM1KMT2A
SCHEMBL1275184 0.78 HSPA5 (0.44) HSPA5HMGCRGAAKMT2AALDH1A1
SCHEMBL1275446 0.78 HSPA5 (0.50) HSPA5HMGCRGAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-7452933-B2 Cross-linked polyethylene having excellent inhibition of sweat-out and insulation properties LG CHEM, LTD. (KR) 2008-11-18 US disclosed
EP-1848768-A4 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
EP-1848768-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG Chem, Ltd. (KR) 2007-10-31 EP disclosed
WO-2007097511-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 WO disclosed
US-20070203278-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 US disclosed