SCHEMBL1275889

SCHEMBL1275889

CC(C)CNC(=O)NCC(C)C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.65
CYP2C19 P33261 1/20 0.65
EPHX1 P07099 2/20 0.61
MAPT P10636 3/20 0.56
MMP1 P03956 1/20 0.54
MMP8 P22894 1/20 0.54
HSD17B10 Q99714 2/20 0.50
KDM4E B2RXH2 2/20 0.50
TP53 P04637 1/20 0.50
LMNA P02545 2/20 0.47
KMT2A Q03164 2/20 0.45
GAA P10253 1/20 0.45
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
TAS1R2 Q8TE23 1/20 0.43
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C9 P11712 1/20 0.41
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL965868 0.89 EPHX1 (0.59) CYP2D6CYP2C19EPHX1MAPTMMP1
SCHEMBL16801793 0.87 CYP2D6 (0.52) CYP2D6CYP2C19EPHX1MAPTMMP1
SCHEMBL15148253 0.87 CYP2D6 (0.52) CYP2D6CYP2C19EPHX1MAPTMMP1
SCHEMBL18782866 0.87 CYP2D6 (0.52) CYP2D6CYP2C19EPHX1MAPTMMP1
SCHEMBL20970337 0.86
SCHEMBL606666 0.86
SCHEMBL16650141 0.85 CYP2D6 (0.56) CYP2D6CYP2C19EPHX1MAPTMMP1
SCHEMBL22361470 0.85 EPHX1 (0.71) CYP2D6CYP2C19EPHX1MAPTMMP1
SCHEMBL10224058 0.85 EPHX1 (0.60) CYP2D6CYP2C19EPHX1MAPTMMP1
SCHEMBL777387 0.84 MAPT (0.59) CYP2D6CYP2C19EPHX1MAPTMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220256854-A1 PLANT TREATMENT COMPOSITION CRODA INTERNATIONAL PLC (GB) 2022-08-18 US claimed
EP-3986135-A1 PLANT TREATMENT COMPOSITION Croda International PLC (GB) 2022-04-27 EP claimed
WO-2020254104-A1 PLANT TREATMENT COMPOSITION CRODA INTERNATIONAL PLC (GB) 2020-12-24 WO claimed
US-20080306237-A1 Highly Functional, Highly Branched Polyureas BASF AKTIENGESELLSCHAFT (DE) 2008-12-11 US claimed
EP-1716197-B1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF SE (DE) 2008-10-29 EP claimed
EP-4315479-A1 METHOD FOR RECYCLING LITHIUM SALTS FROM BATTERIES ARKEMA FRANCE (FR) 2024-02-07 EP disclosed
CN-117063330-A Method for recycling lithium salts from batteries 阿科玛法国公司 2023-11-14 CN disclosed
US-20230227414-A1 Prolyl Hydroxylase Inhibitors GLAXOSMITHKLINE LLC (US) 2023-07-20 US disclosed
US-11643397-B2 Prolyl hydroxylase inhibitors GLAXOSMITHKLINE LLC (US) 2023-05-09 US disclosed
WO-2022207991-A1 METHOD FOR RECYCLING LITHIUM SALTS FROM BATTERIES ARKEMA FRANCE (FR) 2022-10-06 WO disclosed
US-20220256854-A1 PLANT TREATMENT COMPOSITION CRODA INTERNATIONAL PLC (GB) 2022-08-18 US disclosed
EP-3986135-A1 PLANT TREATMENT COMPOSITION Croda International PLC (GB) 2022-04-27 EP disclosed
EP-0992497-A1 1,3-Dialkyl-2-imidazolidinones and a manufacturing process therefor Mitsui Chemicals, Inc. (JP) 2000-04-12 EP disclosed
US-4611079-A USEFUL AS ISOCAYANATE PRECURSORS BASF AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed
US-4581451-A ALKYLATION AND CYCLIZATION OF A URACIL COMPOUND NESTEC S.A. (CH) 1986-04-08 US disclosed
US-4480110-A FROM SUBSTITUTED UREAS AND ALCOHOL BAYER AKTIENGESELLSCHAFT (DE) 1984-10-30 US disclosed
US-4469698-A SEDATIVES, TRANQUILIZERS SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) 1984-09-04 US disclosed
US-4400329-A Process for the manufacture of thiochlorformates SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1983-08-23 US disclosed
US-4388238-A FROM PRIMARY AMINES, ALCOHOLS, AND CARBONYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0039780-A1 Di- or trisubstituted xanthines with neuroleptic activity, process for their preparation and pharmaceutical preparations containing them SOCIETE DES PRODUITS NESTLE S.A. (CH) 1981-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11643397-B2 Prolyl hydroxylase inhibitors HIF1AN, EGLN3, EGLN2 CYP2D6 650/4885CYP2C19 535/4885EPHX1 635/4885
US-20230227414-A1 Prolyl Hydroxylase Inhibitors HIF1AN, EGLN3, EGLN2 CYP2D6 650/4885CYP2C19 535/4885EPHX1 635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.