Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18082556 | 0.89 | BCHE (0.38) | BCHECARM1PRMT6DRD4DRD3 | |
| SCHEMBL12953 | 0.79 | KDM4E (0.42) | DRD3DRD2 | |
| SCHEMBL18082905 | 0.79 | BCHE (0.41) | BCHECARM1PRMT6DRD4DRD3 | |
| SCHEMBL12989 | 0.79 | BCHE (0.41) | BCHECARM1PRMT6DRD4DRD3 | |
| SCHEMBL12449649 | 0.79 | KDM4E (0.42) | DRD3DRD2 | |
| SCHEMBL18082904 | 0.79 | BCHE (0.41) | BCHECARM1PRMT6DRD4DRD3 | |
| SCHEMBL12718237 | 0.79 | BCHE (0.46) | BCHECARM1PRMT6DRD4DRD3 | |
| SCHEMBL12718233 | 0.79 | BCHE (0.46) | BCHECARM1PRMT6DRD4DRD3 | |
| SCHEMBL27297127 | 0.79 | BCHE (0.46) | BCHECARM1PRMT6DRD4DRD3 | |
| SCHEMBL10077156 | 0.78 | DRD4 (0.50) | BCHEDRD4DRD3DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058149-A1 | TRICYCLIC PYRAZOL AMINE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-05-19 | — | — | WO | disclosed |