⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698457 | 0.93 | HCAR2 (0.62) | — | |
| SCHEMBL4369309 | 0.91 | HCAR2 (0.63) | — | |
| SCHEMBL5238456 | 0.91 | HCAR2 (0.63) | — | |
| SCHEMBL8379400 | 0.91 | HCAR2 (0.63) | — | |
| SCHEMBL4371063 | 0.91 | HCAR2 (0.63) | — | |
| SCHEMBL697992 | 0.91 | HCAR2 (0.63) | — | |
| SCHEMBL8390518 | 0.91 | HCAR2 (0.63) | — | |
| SCHEMBL8376821 | 0.91 | HCAR2 (0.63) | — | |
| SCHEMBL1245209 | 0.91 | HCAR2 (0.63) | — | |
| SCHEMBL5239452 | 0.91 | HCAR2 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 886 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107343965-B | Bone adhesive and preparation method thereof | 中国科学院化学研究所 | 2020-04-24 | — | — | CN | claimed |
| US-20200095241-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYLPYRROLONES AND 1,2,4-THIADIAZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | claimed |
| US-20190330192-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-10-31 | — | — | US | claimed |
| EP-3558976-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | Bayer CropScience Aktiengesellschaft (DE) | 2019-10-30 | — | — | EP | claimed |
| EP-3558986-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PYRROLONES AND 1,2,4-THIADIAZOLYL HYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2019-10-30 | — | — | EP | claimed |
| WO-2018114663-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-28 | — | — | WO | claimed |
| WO-2018114662-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PYRROLONES AND 1,2,4-THIADIAZOLYL HYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-28 | — | — | WO | claimed |
| EP-3256448-A1 | SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-12-20 | — | — | EP | claimed |
| WO-2016128365-A1 | SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-08-18 | — | — | WO | claimed |
| WO-2007111933-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HYPOGLYCEMIC AGENT AND METHODS OF USING SAME | INTRANASAL THERAPEUTICS , INC. (US) | 2007-10-04 | — | — | WO | claimed |
| WO-1996003385-A1 | 3,4-SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | claimed |
| US-5486534-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-01-23 | — | — | US | claimed |
| US-5478713-A | Containing specified yellow dye-forming coupler and hydrazine derivative discoloration inhibitor | FUJI PHOTO FILM CO., LTD. (JP) | 1995-12-26 | — | — | US | claimed |
| EP-0274127-B1 | Biologically degradable derivatives of poly(hydroxy alkyl)aminodicarboxylic acid, process for their preparation and their use for sustained release compositions | HOECHST AG (DE) | 1993-12-01 | — | — | EP | claimed |
| US-4960768-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | claimed |
| US-4906473-A | Biodegradable poly(hydroxyalkyl)amino dicarboxylic acid) derivatives, a process for their preparation, and the use thereof for depot formulations with controlled delivery of active ingredient | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | claimed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | claimed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | claimed |
| US-4636242-A | SYMMETRICAL DIALKYL POLYSULFIDE PLASTICIZER | THE O. M. SCOTT AND SONS COMPANY (US) | 1987-01-13 | — | — | US | claimed |
| US-4159379-A | Dispersion dyestuffs of the naphtholactam series | CIBA-GEIGY AG (CH) | 1979-06-26 | — | — | US | claimed |