Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478763 | 0.91 | PDE4B (0.74) | PDE4BCSF1RLRRK2 | |
| SCHEMBL2481381 | 0.87 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL1275589 | 0.82 | PDE4B (0.75) | PDE4BCSF1RLRRK2 | |
| Hydrochloric Acid SCHEMBL2481486 | 0.81 | PDE4B (0.74) | PDE4BCSF1RLRRK2 | |
| SCHEMBL1275366 | 0.81 | PDE4B (0.74) | PDE4BCSF1R | |
| SCHEMBL2484127 | 0.81 | PDE4B (0.73) | PDE4BCSF1RLRRK2 | |
| SCHEMBL1275851 | 0.80 | PDE4B (0.65) | PDE4BCSF1RLRRK2 | |
| SCHEMBL1275607 | 0.79 | PDE4B (0.64) | PDE4BCSF1RLRRK2 | |
| SCHEMBL1275345 | 0.79 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL4949456 | 0.78 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4DCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4625460-B2 | — | — | 2011-02-02 | — | — | JP | claimed |
| JP-2007501264-A | — | — | 2007-01-25 | — | — | JP | claimed |
| EP-1633748-A1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-15 | — | — | EP | claimed |
| WO-2004103998-A1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-02 | — | — | WO | claimed |