Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12705519 | 1.00 | CNR2 (0.37) | CNR2NPC1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL12705523 | 1.00 | CNR2 (0.37) | CNR2NPC1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL10560526 | 0.84 | PRCP (0.41) | NPC1L3MBTL1PRCPHTR2CKDM4E | |
| SCHEMBL172877 | 0.75 | SLC6A2 (0.38) | CNR2SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL12751050 | 0.75 | PRCP (0.39) | NPC1L3MBTL1PRCPMEN1KMT2A | |
| SCHEMBL12705453 | 0.75 | PRCP (0.39) | NPC1L3MBTL1PRCPMEN1KMT2A | |
| SCHEMBL11592473 | 0.73 | SLC6A2 (0.60) | CNR2SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL30998353 | 0.73 | SLC6A2 (0.60) | CNR2SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL11592475 | 0.73 | SLC6A2 (0.60) | CNR2SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL11592479 | 0.73 | SLC6A2 (0.60) | CNR2SLC6A2SLC6A4SLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902187-B2 | 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression | WYETH LLC (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090069289-A1 | 6-SUBSTITUTED 2-(BENZIMIDAZOLYL)PURINE AND PURINONE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069289-A1 | 6-SUBSTITUTED 2-(BENZIMIDAZOLYL)PURINE AND PURINONE DERIVATIVES FOR IMMUNOSUPPRESSION | P2RY6, P2RY1, P2RX6 | CNR2 118/4885NPC1 2782/4885L3MBTL1 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.