Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.41 |
| ▸ | CA2 | P00918 | 9/20 | 0.41 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987798 | 1.00 | CA1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL987423 | 1.00 | CA1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL723644 | 1.00 | CA1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL718849 | 0.98 | CA1 (0.40) | CA1CA2CA9CA12CA7 | |
| SCHEMBL9079331 | 0.92 | TP53 (0.38) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL7132558 | 0.91 | TP53 (0.37) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1276367 | 0.85 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL719166 | 0.85 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL717340 | 0.85 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL721790 | 0.85 | CA1 (0.44) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464644-A1 | SOLID ORAL FORMULATIONS AND CRYSTALLINE FORMS OF AN INHIBITOR OF APOPTOSIS PROTEIN | Novartis AG (CH) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011018474-A1 | SOLID ORAL FORMULATIONS AND CRYSTALLINE FORMS OF AN INHIBITOR OF APOPTOSIS PROTEIN | NOVARTIS AG (CH) | 2011-02-17 | — | — | WO | disclosed |
| WO-2001091716-A1 | PERORAL THERAPEUTIC SYSTEM COMPRISING GLIPIZIDE | ADD ADVANCED DRUG DELIVERY TECHNOLOGIES AG (CH) | 2001-12-06 | — | — | WO | disclosed |