Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972840 | 0.85 | CYP1A2 (0.33) | — | |
| SCHEMBL9924205 | 0.76 | ECE1 (0.41) | — | |
| SCHEMBL12990094 | 0.73 | SLC22A6 (0.46) | SLC22A6GPR84 | |
| SCHEMBL15468382 | 0.72 | FOLH1 (0.48) | — | |
| SCHEMBL9924203 | 0.72 | KDM4E (0.47) | — | |
| SCHEMBL8769052 | 0.70 | SLC22A6 (0.52) | SLC22A6GPR84 | |
| SCHEMBL2907101 | 0.70 | SLC22A6 (0.52) | SLC22A6GPR84 | |
| SCHEMBL2130208 | 0.70 | SLC22A6 (0.52) | SLC22A6GPR84 | |
| SCHEMBL9972829 | 0.70 | — | — | |
| SCHEMBL12764402 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897376-B2 | Lysis reagents comprising at least two trialkylammonioalkylsulfonates, and a capture ligand specific for the target coating the interior surface of a multiwell plate; one step extraction not requiring centrifugation of the cellular solution | SIGMA-ALDRICH CO. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7799561-B2 | Affinity peptides and method for purification of recombinant proteins | SIGMA-ALDRICH, CO. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7741053-B2 | Processes for purification of recombinant proteins | SIGMA-ALDRICH CO. (US) | 2010-06-22 | — | — | US | disclosed |
| US-7709612-B2 | Metal chelating compositions for protein purification, detection or binding | SIGMA-ALDRICH CO. (US) | 2010-05-04 | — | — | US | disclosed |
| US-20080064093-A1 | COMPOSITIONS AND METHODS EMPLOYING ZWITTERIONIC DETERGENT COMBINATIONS | SIGMA ALDRICH COMPANY (US) | 2008-03-13 | — | — | US | disclosed |
| US-7282475-B2 | Compositions and methods employing zwitterionic detergent combinations | SIGMA-ALDRICH CO. (US) | 2007-10-16 | — | — | US | disclosed |