Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979139 | 0.90 | MAPT (0.53) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL1519613 | 0.90 | PTGS1 (0.41) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL1519474 | 0.87 | PTGS1 (0.50) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL12837394 | 0.87 | MAPT (0.54) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL1519369 | 0.86 | MAPT (0.51) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL13274249 | 0.85 | MAPT (0.52) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL13274415 | 0.84 | MAPT (0.51) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL7011092 | 0.83 | CA12 (0.57) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL6315710 | 0.83 | CA12 (0.57) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL15486527 | 0.83 | MAPT (0.61) | PTGS1PTGS2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897560-B2 | Plasma protein affinity tags | NOVO NORDISK A/S (DK) | 2011-03-01 | — | — | US | disclosed |
| US-20100184641-A1 | Novel Plasma Protein Affinity Tags | NOVO NORDISK A/S (DK) | 2010-07-22 | — | — | US | disclosed |
| US-20100184641-A1 | Novel Plasma Protein Affinity Tags | NOVO NORDISK A/S (DK) | 2010-07-22 | — | — | US | disclosed |
| US-7541430-B2 | Peptides for use in treating obesity | NOVO NORDISK A/S (DK) | 2009-06-02 | — | — | US | disclosed |
| US-20090088388-A1 | Peptides for Use In Treating Obesity | NOVO NORDISK A/S (DK) | 2009-04-02 | — | — | US | disclosed |
| US-20070244054-A1 | Peptides for use in treating obesity | NOVO NORDISK A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| US-20070244054-A1 | Peptides for use in treating obesity | NOVO NORDISK A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| US-20070105750-A1 | Novel plasma protein affinity tags | NOVO NORDISK A/S (DK) | 2007-05-10 | — | — | US | disclosed |
| US-20070105750-A1 | Novel plasma protein affinity tags | NOVO NORDISK A/S (DK) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184641-A1 | Novel Plasma Protein Affinity Tags | CD2BP2, HDLBP, SERPINA6 | PTGS1 4520/4885PTGS2 4581/4885CA12 4761/4885 |
| US-20070105750-A1 | Novel plasma protein affinity tags | CD2BP2, HDLBP, SERPINA6 | PTGS1 4520/4885PTGS2 4581/4885CA12 4761/4885 |
| US-20070244054-A1 | Peptides for use in treating obesity | NPY4R, GLP1R, NPY1R | PTGS1 3932/4885PTGS2 4649/4885CA12 3488/4885 |
| US-20090088388-A1 | Peptides for Use In Treating Obesity | NPY4R, GLP1R, NPY1R | PTGS1 3932/4885PTGS2 4649/4885CA12 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.