Thiofanox

Thiofanox

SCHEMBL1276544

CNC(=O)O/N=C(/C)SCCC#N.CNC(=O)ON=C(CSC)C(C)(C)C

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxamyl SCHEMBL19032724 0.90
SCHEMBL119987 0.85 MCL1 (0.32) TDP1
SCHEMBL9326558 0.85 MCL1 (0.32) TDP1
SCHEMBL5933883 0.85 MCL1 (0.32) TDP1
Thiofanox SCHEMBL19643391 0.84
SCHEMBL11680595 0.82 TDP1 (0.33) TDP1
Carbamic Acid SCHEMBL11127389 0.81
Thiofanox SCHEMBL122112 0.81 TDP1 (0.44) TDP1
Thiofanox SCHEMBL7528288 0.81 TDP1 (0.44) TDP1
Thiofanox SCHEMBL8397784 0.81 TDP1 (0.44) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285741-A2 SILICA DISPERSION Evonik Degussa GmbH (DE) 2011-02-23 EP disclosed
WO-2009095139-A2 SILICA DISPERSION EVONIK DEGUSSA GMBH (DE) 2009-08-06 WO disclosed