Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.69 |
| ▸ | CD38 | P28907 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | GUSB | P08236 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638609 | 1.00 | MEN1 (0.72) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL1638612 | 1.00 | MEN1 (0.72) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL1639422 | 0.89 | NTRK1 (0.81) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL10049700 | 0.89 | NTRK1 (0.81) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL1639424 | 0.89 | NTRK1 (0.81) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL29695425 | 0.89 | NTRK1 (0.81) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL13971452 | 0.87 | MEN1 (0.68) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL1637247 | 0.85 | MEN1 (0.66) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL1637249 | 0.85 | MEN1 (0.66) | MEN1KMT2AKDM4ETP53CYP3A4 | |
| SCHEMBL12766748 | 0.85 | MEN1 (0.66) | MEN1KMT2AKDM4ETP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098309-A1 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-BETA DIFFUSABLE LIGANDS USING ACYLHYDRAZIDE COMPOUNDS | ACUMEN PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098309-A1 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-BETA DIFFUSABLE LIGANDS USING ACYLHYDRAZIDE COMPOUNDS | APP, APBA1, BACE1 | MEN1 2974/4885KMT2A 3625/4885KDM4E 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.