Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345552 | 0.81 | PTGS1 (0.56) | PTGS1HDAC4HDAC8CYP2D6MEN1 | |
| SCHEMBL11063307 | 0.81 | PTGS1 (0.56) | PTGS1HDAC4HDAC8CYP2D6MEN1 | |
| SCHEMBL12767607 | 0.80 | NSD2 (0.55) | NSD2HSP90AA1HKDC1TLR9CYP2D6 | |
| SCHEMBL765113 | 0.80 | PTGS1 (0.66) | PTGS1CYP2D6MEN1KMT2ACASP1 | |
| SCHEMBL30358257 | 0.80 | PTGS1 (0.66) | PTGS1CYP2D6MEN1KMT2ACASP1 | |
| SCHEMBL15849013 | 0.79 | PTGS1 (0.55) | PTGS1HDAC4HDAC8CYP2D6MEN1 | |
| SCHEMBL19409298 | 0.79 | TDP1 (0.54) | PTGS1NSD2HSP90AA1HKDC1TLR9 | |
| SCHEMBL123764 | 0.77 | PTGS1 (0.58) | PTGS1HDAC4HDAC8CYP2D6MEN1 | |
| SCHEMBL26473527 | 0.77 | HDAC4 (0.41) | PTGS1HDAC4HDAC8CASP1 | |
| SCHEMBL14665631 | 0.77 | HTT (0.60) | PTGS1CYP2D6MEN1KMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42189-E1 | Single-layer type electrophotosensitive material and image forming apparatus using the same | KYOCERA MITA CORPORATION (JP) | 2011-03-01 | — | — | US | disclosed |
| US-RE42189-E1 | Single-layer type electrophotosensitive material and image forming apparatus using the same | KYOCERA MITA CORPORATION (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20080286673-A1 | Single layer type electrophotographic photoconductor and image forming device | KYOCERA MITA CORPORATION | 2008-11-20 | — | — | US | disclosed |
| US-20080286673-A1 | Single layer type electrophotographic photoconductor and image forming device | KYOCERA MITA CORPORATION | 2008-11-20 | — | — | US | disclosed |
| US-7416825-B2 | Single layer type electrophotographic photoconductor and image forming device | KYOCERA MITA CORPORATION (JP) | 2008-08-26 | — | — | US | disclosed |
| US-7416825-B2 | Single layer type electrophotographic photoconductor and image forming device | KYOCERA MITA CORPORATION (JP) | 2008-08-26 | — | — | US | disclosed |
| US-RE39516-E1 | Single-layer type electrophotosensitive material and image forming apparatus using the same | KYOCERA MITA CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| US-RE39516-E1 | Single-layer type electrophotosensitive material and image forming apparatus using the same | KYOCERA MITA CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |