Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639033 | 0.90 | P2RY12 (0.48) | MAPK1MAPK3P2RY12KDM4EALDH1A1 | |
| SCHEMBL12768943 | 0.90 | P2RY12 (0.47) | MAPK1MAPK3P2RY12KDM4EALDH1A1 | |
| SCHEMBL12727461 | 0.89 | P2RY12 (0.47) | MAPK1MAPK3P2RY12KDM4EALDH1A1 | |
| SCHEMBL1639086 | 0.85 | P2RY12 (0.44) | MAPK1MAPK3P2RY12KDM4EALDH1A1 | |
| SCHEMBL1639567 | 0.82 | P2RY12 (0.49) | P2RY12KDM4ESMN1; SMN2B3GNT2GAA | |
| SCHEMBL27756390 | 0.82 | P2RY12 (0.53) | MAPK1MAPK3P2RY12KDM4EALDH1A1 | |
| SCHEMBL12768050 | 0.81 | P2RY12 (0.49) | P2RY12KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13074039 | 0.80 | P2RY12 (0.44) | P2RY12KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12727460 | 0.80 | MAPK3 (0.42) | MAPK1MAPK3P2RY12KDM4EALDH1A1 | |
| SCHEMBL1640679 | 0.80 | P2RY12 (0.46) | MAPK1MAPK3P2RY12KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098247-A1 | Substituted Dihydroquinazolines as Platelet ADP Receptor Inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098247-A1 | Substituted Dihydroquinazolines as Platelet ADP Receptor Inhibitors | TBXA2R, F2R, PTGER1 | MAPK1 562/4885MAPK3 2351/4885P2RY12 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.