Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12770854 | 0.89 | — | — | |
| SCHEMBL13156627 | 0.85 | — | — | |
| SCHEMBL12770790 | 0.85 | — | — | |
| SCHEMBL12552178 | 0.79 | — | — | |
| SCHEMBL15385406 | 0.78 | — | — | |
| SCHEMBL15385407 | 0.78 | — | — | |
| SCHEMBL12553919 | 0.78 | — | — | |
| SCHEMBL13904131 | 0.78 | SMYD2 (0.37) | CYP3A4 | |
| SCHEMBL13904130 | 0.78 | SMYD2 (0.37) | CYP3A4 | |
| SCHEMBL12772093 | 0.78 | SMYD2 (0.37) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915306-B2 | For therapy of inflammatory or autoimmune disorders | EISAI CO., LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| US-7799827-B2 | Macrocyclic compounds useful as pharmaceuticals | EISAI CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |