Sugi Predict

Sugi Predict / Compounds / SCHEMBL12771007

SCHEMBL12771007

SCHEMBL12771007

Cc1ccc(O)c(Pc2ccccc2/C=N/n2cccc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AMY1A P0DUB6 3/20 0.36
▸ MAPT P10636 5/20 0.35
▸ LMNA P02545 5/20 0.35
▸ KDM4E B2RXH2 4/20 0.35
▸ HTT P42858 3/20 0.35
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ POLB P06746 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ PIK3CG P48736 1/20 0.33
▸ DHODH Q02127 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12771002 0.85 POLB (0.40) AMY1AMAPTLMNAKDM4EALDH1A1
SCHEMBL12771008 0.84 MAPT (0.36) AMY1AMAPTLMNAKDM4EALDH1A1
SCHEMBL12770993 0.82 GAA (0.51) MAPTKDM4EHTTALDH1A1HPGD
SCHEMBL12770888 0.82 MAPT (0.39) MAPTLMNAKDM4EHTTALDH1A1
SCHEMBL12771005 0.80 SMN1; SMN2 (0.38) AMY1AMAPTLMNAHTTALDH1A1
SCHEMBL12771000 0.79 GAA (0.39) MAPTLMNAKDM4EHTTALDH1A1
SCHEMBL12770891 0.79 MAOB (0.47) MAPTLMNAKDM4EHTTALDH1A1
SCHEMBL12770954 0.79 MAPT (0.40) MAPTLMNAKDM4EHTTALDH1A1
SCHEMBL12771151 0.78 KDM4E (0.33) AMY1AMAPTKDM4EALDH1A1HPGD
SCHEMBL12771161 0.76 TRIM24 (0.43) LMNAHTTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 — — US disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 — — US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 — — US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 AMY1A 910/4885MAPT 2719/4885LMNA 3039/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 AMY1A 910/4885MAPT 2719/4885LMNA 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.