Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.60 |
| ▸ | PPARA | Q07869 | 9/20 | 0.60 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277670 | 1.00 | PPARG (0.60) | PPARGPPARAPPARDACECACNA1B | |
| SCHEMBL3032276 | 0.86 | PPARG (0.64) | PPARGPPARAPPARDACECACNA1B | |
| SCHEMBL3032280 | 0.86 | PPARG (0.64) | PPARGPPARAPPARDACECACNA1B | |
| SCHEMBL1277769 | 0.86 | PPARG (0.64) | PPARGPPARAPPARDACECACNA1B | |
| SCHEMBL1633974 | 0.85 | PPARG (0.46) | PPARGPPARAACEGAAALDH1A1 | |
| SCHEMBL1632949 | 0.85 | PPARG (0.46) | PPARGPPARAACEGAAALDH1A1 | |
| SCHEMBL10511874 | 0.84 | PPARG (0.62) | PPARGPPARAPPARDACECACNA1B | |
| SCHEMBL1277888 | 0.84 | PPARG (0.62) | PPARGPPARAPPARDACECACNA1B | |
| SCHEMBL1277885 | 0.84 | PPARG (0.62) | PPARGPPARAPPARDACECACNA1B | |
| SCHEMBL1277844 | 0.81 | PPARG (0.74) | PPARGPPARAPPARDACECACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088760-A1 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG CHEM, LTD. (KR) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088760-A1 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | GCKR, GCK, GALK1 | PPARG 1086/4885PPARA 1986/4885PPARD 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.