Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12779105 | 0.89 | NPC1 (0.49) | NPC1RAB9AS1PR1PPARGPPARA | |
| SCHEMBL12779122 | 0.89 | NPC1 (0.46) | NPC1RAB9AS1PR1PPARGPPARA | |
| SCHEMBL12779096 | 0.85 | NPC1 (0.46) | NPC1RAB9APPARGPPARAMRGPRX4 | |
| SCHEMBL12779102 | 0.82 | MAPT (0.49) | NPC1RAB9AS1PR1PPARGPPARA | |
| SCHEMBL12778430 | 0.81 | NPC1 (0.42) | NPC1RAB9APPARGPPARAMAOB | |
| SCHEMBL12779173 | 0.80 | MAPT (0.41) | NPC1RAB9AS1PR1 | |
| SCHEMBL14347664 | 0.80 | PPARG (0.42) | NPC1RAB9APPARGNR1H4MGLL | |
| SCHEMBL12779091 | 0.79 | SLC6A4 (0.42) | NPC1RAB9AS1PR1PPARGPPARA | |
| SCHEMBL12779177 | 0.79 | P2RX1 (0.41) | NPC1RAB9AS1PR1MRGPRX4 | |
| SCHEMBL12779118 | 0.79 | MAPT (0.39) | NPC1RAB9AMRGPRX4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |