Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | FURIN | P09958 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12731305 | 1.00 | ASF1A (0.66) | ASF1AMAPTGAAALDH1A1POLB | |
| SCHEMBL13568634 | 0.89 | ASF1A (0.81) | ASF1AMAPTGAAALDH1A1POLB | |
| SCHEMBL13568887 | 0.82 | ASF1A (0.68) | ASF1AMAPTGAAALDH1A1POLB | |
| SCHEMBL13568639 | 0.81 | ASF1A (0.66) | ASF1AMAPTGAAALDH1A1POLB | |
| SCHEMBL27178310 | 0.81 | ASF1A (0.66) | ASF1AMAPTGAAALDH1A1POLB | |
| SCHEMBL27178313 | 0.81 | ASF1A (0.66) | ASF1AMAPTGAAALDH1A1POLB | |
| SCHEMBL2989526 | 0.79 | ASF1A (0.60) | ASF1AMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL13568666 | 0.79 | MAPT (0.56) | ASF1AMAPTGAAALDH1A1POLB | |
| SCHEMBL2989529 | 0.79 | ASF1A (0.60) | ASF1AMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL13568667 | 0.78 | MAPT (0.51) | MAPTGAAALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047025-A1 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | DOW AGROSCIENCES LLC (US) | 2011-04-21 | — | — | WO | disclosed |
| WO-2009146079-A2 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | DOW AGROSCIENCES LLC (US) | 2009-12-03 | — | — | WO | disclosed |