Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.71 |
| ▸ | IL6 | P05231 | 13/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146552 | 0.85 | TLR7 (0.85) | TLR7IL6 | |
| SCHEMBL15177549 | 0.85 | TLR7 (0.70) | TLR7IL6 | |
| SCHEMBL12800359 | 0.85 | TLR7 (0.70) | TLR7IL6 | |
| SCHEMBL26354123 | 0.85 | TLR7 (0.77) | TLR7IL6 | |
| SCHEMBL1146053 | 0.84 | TLR7 (0.77) | TLR7IL6 | |
| SCHEMBL12800331 | 0.83 | TLR7 (0.73) | TLR7IL6 | |
| SCHEMBL1146409 | 0.83 | TLR7 (0.81) | TLR7IL6 | |
| SCHEMBL1344409 | 0.83 | TLR7 (0.73) | TLR7IL6 | |
| SCHEMBL15500435 | 0.82 | TLR7 (0.67) | TLR7IL6 | |
| SCHEMBL1145806 | 0.82 | TLR7 (0.77) | TLR7IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011049825-A1 | DERIVATIVES OF PURINE OR DEAZAPURINE USEFUL FOR THE TREATMENT OF (INTER ALIA) VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2011-04-28 | — | — | WO | disclosed |