Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 13/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15263332 | 0.92 | EPHX1 (0.57) | EPHX2EPHX1KDM4EALDH1A1KDM1A | |
| SCHEMBL965926 | 0.92 | — | — | |
| SCHEMBL1908654 | 0.84 | EPHX1 (0.50) | EPHX2EPHX1KDM4EALDH1A1KDM1A | |
| SCHEMBL20233001 | 0.84 | EPHX1 (0.60) | EPHX2EPHX1KDM4EALDH1A1KDM1A | |
| SCHEMBL968340 | 0.83 | EPHX1 (0.63) | EPHX2EPHX1KDM4EALDH1A1KMT2A | |
| SCHEMBL965080 | 0.83 | EPHX1 (0.69) | EPHX2EPHX1KDM4EALDH1A1 | |
| SCHEMBL10802279 | 0.82 | SMYD3 (0.50) | EPHX2EPHX1KDM4EALDH1A1KDM1A | |
| SCHEMBL20232809 | 0.82 | EPHX2 (0.51) | EPHX2EPHX1KDM4EALDH1A1KDM1A | |
| SCHEMBL13179208 | 0.82 | EPHX2 (0.51) | EPHX2EPHX1KDM4EALDH1A1KDM1A | |
| SCHEMBL13480574 | 0.82 | EPHX1 (0.72) | EPHX2EPHX1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046970-A1 | AMINO - PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBKL AND/OR IKK EPSILON | MYREXIS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |