Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 11/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2109534 | 0.88 | PRSS1 (0.62) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL13835862 | 0.88 | PRSS1 (0.54) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL12801833 | 0.85 | PRSS1 (0.51) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL13835533 | 0.82 | PRSS1 (0.54) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL13835805 | 0.81 | PRSS1 (0.56) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2110944 | 0.79 | PRSS1 (0.63) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL19387481 | 0.78 | PRSS1 (0.49) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL12601735 | 0.77 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2110664 | 0.77 | PRSS1 (0.82) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109979 | 0.77 | PRSS1 (0.59) | PRSS1PRSS2PRSS3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |