SCHEMBL12801946

SCHEMBL12801946

COc1ccc([C@@H]2O[C@H](C)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc2c(c1)NCCS2

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 18/20 0.50
SLC5A1 P13866 8/20 0.50
SELP P16109 2/20 0.41
SELL P14151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1670794 0.90 SLC5A2 (0.65) SLC5A2SLC5A1
SCHEMBL12801879 0.87 SLC5A2 (0.58) SLC5A2SLC5A1
SCHEMBL13278605 0.78 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL17189354 0.77 SLC5A2 (0.64) SLC5A2SLC5A1SELPSELL
SCHEMBL1670032 0.76 SLC5A2 (0.73) SLC5A2SLC5A1
SCHEMBL17189349 0.74 SLC5A2 (0.77) SLC5A2SLC5A1
SCHEMBL14108357 0.74 SLC5A2 (0.77) SLC5A2SLC5A1
SCHEMBL15015428 0.73 SLC5A2 (0.74) SLC5A2SLC5A1
SCHEMBL1672730 0.73 SLC5A2 (0.74) SLC5A2SLC5A1
SCHEMBL29657282 0.73 SLC5A2 (0.66) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011048112-A1 GLYCOSIDE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2011-04-28 WO disclosed