SCHEMBL12802115

SCHEMBL12802115

C=C/C=C/c1ccccc1CCCC

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
THRA P10827 2/20 0.39
THRB P10828 2/20 0.39
LIPG Q9Y5X9 1/20 0.39
TLR8 Q9NR97 1/20 0.34
PTGER4 P35408 2/20 0.33
PTGER3 P43115 2/20 0.33
PTGER2 P43116 2/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
TYR P14679 1/20 0.33
CDK4 P11802 1/20 0.32
CCND1 P24385 1/20 0.32
TSHR P16473 1/20 0.32
ALOX5 P09917 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12802118 1.00 CYP3A4 (0.40) CYP3A4CYP2D6CYP2C9THRATHRB
SCHEMBL12802288 0.89 CDK4 (0.33) THRATHRBLIPGCDK4CCND1
SCHEMBL12802287 0.89 CDK4 (0.33) THRATHRBLIPGCDK4CCND1
SCHEMBL113477 0.83 CDK4 (0.48) CYP3A4CYP2D6CYP2C9THRATHRB
SCHEMBL2938850 0.83 CDK4 (0.48) CYP3A4CYP2D6CYP2C9THRATHRB
SCHEMBL30918142 0.83 CDK4 (0.48) CYP3A4CYP2D6CYP2C9THRATHRB
SCHEMBL28869 0.82 CYP3A4 (0.44) CYP3A4CYP2D6CYP2C9THRATHRB
SCHEMBL29480441 0.82 CYP3A4 (0.44) CYP3A4CYP2D6CYP2C9THRATHRB
SCHEMBL14452362 0.82 CDK4 (0.38) PTGER4PTGER3PTGER2CDK4CCND1
SCHEMBL12802431 0.82 CDK4 (0.38) PTGER4PTGER3PTGER2CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9587042-B2 Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-07 US disclosed
US-8933165-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-13 US disclosed
US-8835564-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-16 US disclosed
US-20140088242-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
US-20140088256-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
US-20120252966-A1 PROCESS FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-10-04 US disclosed