Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 4/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12235930 | 0.82 | NR3C2 (0.45) | NR3C2SYKMAP3K7FFAR2LRRK2 | |
| SCHEMBL2744990 | 0.82 | NR3C2 (0.45) | NR3C2SYKMAP3K7FFAR2LRRK2 | |
| SCHEMBL12235349 | 0.82 | NR3C2 (0.45) | NR3C2SYKMAP3K7FFAR2LRRK2 | |
| SCHEMBL14376036 | 0.81 | NR3C2 (0.47) | WNT3ANR3C2SYKATMMAP3K7 | |
| SCHEMBL21588462 | 0.79 | AKR1C3 (0.46) | WNT3ANR3C2SYKMAP3K7LRRK2 | |
| SCHEMBL21588456 | 0.79 | AKR1C3 (0.46) | WNT3ANR3C2SYKMAP3K7LRRK2 | |
| SCHEMBL21588286 | 0.79 | AKR1C3 (0.46) | WNT3ANR3C2SYKMAP3K7LRRK2 | |
| SCHEMBL27034072 | 0.79 | MAPT (0.45) | CHIA | |
| SCHEMBL27239071 | 0.79 | MAPT (0.45) | CHIA | |
| SCHEMBL21396407 | 0.79 | ATM (0.38) | NR3C2SYKATMFFAR2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120251551-A1 | Substituted (Heteroarylmethyl)thiohydantoins | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120251551-A1 | Substituted (Heteroarylmethyl)thiohydantoins | TPMT, BPHL, VHL | WNT3A 4115/4885NR3C2 290/4885CHIA 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.