Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791353 | 0.91 | GAA (0.35) | GAAADRB3ADRA2BADRA2CCTSD | |
| SCHEMBL3791354 | 0.91 | GAA (0.35) | GAAADRB3ADRA2BADRA2CCTSD | |
| SCHEMBL2624064 | 0.88 | ADRB3 (0.45) | GAAADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL5530647 | 0.88 | ADRB3 (0.45) | GAAADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL3058266 | 0.88 | ADRB3 (0.45) | GAAADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL5534012 | 0.88 | ADRB3 (0.45) | GAAADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL5534015 | 0.88 | ADRB3 (0.45) | GAAADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL7876742 | 0.88 | ADRB3 (0.45) | GAAADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL5530641 | 0.88 | ADRB3 (0.45) | GAAADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL4955686 | 0.88 | ADRB3 (0.45) | GAAADRB3ADRA2BADRA2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305695-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |