Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 15/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 9/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13088371 | 0.90 | SLC5A2 (0.43) | SLC5A2SLC5A1ACHE | |
| SCHEMBL13088364 | 0.89 | SLC5A2 (0.40) | SLC5A2SLC5A1ACHETYRCYP1A2 | |
| SCHEMBL13088365 | 0.89 | SLC5A2 (0.53) | SLC5A2SLC5A1ACHE | |
| SCHEMBL13088375 | 0.89 | SLC5A2 (0.46) | SLC5A2SLC5A1ACHE | |
| SCHEMBL13088372 | 0.89 | SLC5A2 (0.40) | SLC5A2SLC5A1ACHETYRCYP1A2 | |
| SCHEMBL13088368 | 0.89 | SLC5A2 (0.47) | SLC5A2SLC5A1ACHE | |
| SCHEMBL12808213 | 0.87 | SLC5A2 (0.54) | SLC5A2SLC5A1ACHE | |
| SCHEMBL13088380 | 0.86 | SLC5A2 (0.48) | SLC5A2SLC5A1ACHE | |
| SCHEMBL13098422 | 0.85 | SLC5A2 (0.41) | SLC5A2SLC5A1TYR | |
| SCHEMBL13088373 | 0.85 | SLC5A2 (0.41) | SLC5A2SLC5A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011039338-A2 | USE OF COMPOUNDS WITH SGLT-1/SGLT-2 INHIBITOR ACTIVITY FOR PRODUCING MEDICAMENTS FOR TREATMENT OF BONE DISEASES | SANOFI-AVENTIS (FR) | 2011-04-07 | — | — | WO | disclosed |