Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799932 | 0.95 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13563487 | 0.94 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL3788175 | 0.92 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13563489 | 0.91 | DDB1 (0.31) | DDB1CRBN | |
| SCHEMBL11983950 | 0.91 | DDB1 (0.33) | DDB1CRBN | |
| SCHEMBL11975889 | 0.91 | DDB1 (0.33) | DDB1CRBN | |
| SCHEMBL13059149 | 0.91 | DDB1 (0.33) | DDB1CRBN | |
| SCHEMBL13563493 | 0.91 | DDB1 (0.31) | DDB1CRBN | |
| SCHEMBL3796413 | 0.91 | DDB1 (0.31) | DDB1CRBN | |
| SCHEMBL11976188 | 0.89 | CYP3A4 (0.32) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305697-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |