Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12601257 | 0.94 | S1PR1 (0.54) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL1398466 | 0.88 | S1PR1 (0.71) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL1398430 | 0.87 | S1PR1 (0.68) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL2048791 | 0.86 | S1PR1 (0.67) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL2054001 | 0.85 | S1PR1 (0.59) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL1398629 | 0.85 | S1PR1 (0.59) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL13644176 | 0.85 | S1PR1 (0.54) | S1PR1S1PR3 | |
| SCHEMBL1981338 | 0.84 | S1PR1 (0.58) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL1398517 | 0.84 | S1PR1 (0.57) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL2054003 | 0.78 | S1PR1 (0.64) | S1PR1CYP2C9S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137181-B1 | OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE (S1P) AGONISTS | GLAXO GROUP LTD (GB) | 2011-03-02 | — | — | EP | disclosed |