SCHEMBL12809484

SCHEMBL12809484

C[C@@H]1CCCN1CCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 19/20 0.60
TERT O14746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9489055 1.00 HRH3 (0.60) HRH3TERT
SCHEMBL499914 0.94 HRH3 (0.55) HRH3TERT
SCHEMBL1856917 0.89 HRH3 (0.62) HRH3
SCHEMBL1861972 0.89 HRH3 (0.62) HRH3
SCHEMBL1858200 0.89 HRH3 (0.62) HRH3
SCHEMBL29044106 0.88 HRH3 (0.48) HRH3TERT
SCHEMBL17598220 0.87 HRH3 (0.60) HRH3
SCHEMBL27894809 0.86 HRH3 (0.59) HRH3
SCHEMBL27894808 0.86 HRH3 (0.59) HRH3
SCHEMBL27894811 0.86 HRH3 (0.59) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620434-B1 FUSED BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS ABBOTT LAB (US) 2011-03-09 EP disclosed