Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.73 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.70 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807479 | 0.95 | TDP1 (0.77) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL29928558 | 0.92 | TDP1 (0.75) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL10044328 | 0.90 | TDP1 (0.72) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL27233227 | 0.88 | TDP1 (0.69) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL27233233 | 0.88 | TDP1 (0.69) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL3773934 | 0.87 | TDP1 (0.68) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL12098624 | 0.87 | TDP1 (0.83) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL8525642 | 0.87 | TDP1 (0.67) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL13227941 | 0.87 | TDP1 (0.67) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL15353872 | 0.87 | TDP1 (0.64) | TDP1FOLH1CAPN1MEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1830887-B1 | ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN RESIDUE | ORGANON NV (NL) | 2011-03-09 | — | — | EP | disclosed |