Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 9/20 | 0.71 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2624922 | 0.85 | KCNA5 (0.71) | KCNA5SCN5ASLC6A4KCND2SLC18A3 | |
| SCHEMBL3584661 | 0.85 | KCNA5 (0.71) | KCNA5SCN5ASLC6A4KCND2SLC18A3 | |
| SCHEMBL1762216 | 0.85 | KCNA5 (0.71) | KCNA5SCN5ASLC6A4KCND2SLC18A3 | |
| SCHEMBL14434183 | 0.85 | KCNA5 (0.71) | KCNA5SCN5ASLC6A4KCND2KCNH2 | |
| SCHEMBL1762201 | 0.85 | KCNA5 (0.71) | KCNA5SCN5ASLC6A4KCND2SLC18A3 | |
| Hydrochloric Acid SCHEMBL909033 | 0.84 | KCNA5 (0.70) | KCNA5SCN5ASLC6A4KCND2KCNH2 | |
| Hydrochloric Acid SCHEMBL909031 | 0.84 | KCNA5 (0.70) | KCNA5SCN5ASLC6A4KCND2KCNH2 | |
| SCHEMBL6807137 | 0.83 | KCNA5 (1.00) | KCNA5SCN5ASLC6A4 | |
| SCHEMBL12391697 | 0.83 | KCNA5 (1.00) | KCNA5SCN5ASLC6A4 | |
| SCHEMBL2624914 | 0.83 | KCNA5 (1.00) | KCNA5SCN5ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298735-A1 | Aminocyclohexyl ether compounds and uses thereof | Cardiome Pharma Corp. (CA) | 2011-03-23 | — | — | EP | disclosed |