Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.63 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.63 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | IL1B | P01584 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14072311 | 0.89 | DDB1 (0.67) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL1424768 | 0.87 | DDB1 (0.65) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL12811257 | 0.87 | DDB1 (0.58) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL1424490 | 0.86 | DDB1 (0.66) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL12811084 | 0.85 | DDB1 (0.60) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL1424625 | 0.85 | DDB1 (0.62) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL15468278 | 0.85 | DDB1 (0.64) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL1424373 | 0.84 | DDB1 (0.64) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL14072380 | 0.84 | DDB1 (0.63) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL1424577 | 0.83 | DDB1 (0.67) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076260-B1 | N-METHYLAMINOMETHYL ISOINDOLE COMPOUNDS AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | CELGENE CORP (US) | 2011-03-23 | — | — | EP | disclosed |