Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12788021 | 0.89 | TP53 (0.41) | TP53GALR3AURKARPS6KB1RAB9A | |
| SCHEMBL12788250 | 0.88 | TP53 (0.47) | TP53AURKARPS6KB1HTTSMN1; SMN2 | |
| SCHEMBL12811343 | 0.88 | PIK3CD (0.35) | RAB9AHTTLMNAKMT2A | |
| SCHEMBL1437346 | 0.87 | TP53 (0.39) | TP53AURKARPS6KB1HTTSMN1; SMN2 | |
| SCHEMBL12811361 | 0.87 | MAPT (0.41) | TP53GALR3RAB9AHTTSMN1; SMN2 | |
| SCHEMBL6525751 | 0.87 | TP53 (0.39) | TP53GALR3AURKARPS6KB1HTT | |
| SCHEMBL12788862 | 0.87 | TP53 (0.39) | TP53GALR3AURKARPS6KB1HTT | |
| SCHEMBL12811456 | 0.85 | KDM4E (0.42) | TP53NFKB1NFKB2RELAGALR3 | |
| SCHEMBL12811751 | 0.85 | MAPT (0.51) | GALR3RAB9AHTTSMN1; SMN2TSHR | |
| SCHEMBL12788025 | 0.85 | TP53 (0.38) | TP53GALR3AURKARPS6KB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025505-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | WO | disclosed |