Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 14/20 | 0.68 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13427602 | 0.84 | KCNN4 (0.44) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL2338402 | 0.82 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL18782528 | 0.78 | KCNN4 (0.81) | KCNN4KCNE1KCNQ1ALDH1A1 | |
| SCHEMBL12812142 | 0.77 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL1443978 | 0.77 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1CES2CES1 | |
| Senicapoc SCHEMBL1443805 | 0.75 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1 | |
| SCHEMBL2337394 | 0.75 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1 | |
| SCHEMBL13928001 | 0.74 | KCNN4 (0.81) | KCNN4KCNE1KCNQ1 | |
| SCHEMBL14437487 | 0.73 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1 | |
| SCHEMBL18782529 | 0.71 | KCNN4 (0.75) | KCNN4KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070536-A1 | METHODS AND AGENTS FOR TREATING DISEASES | ANGION BIOMEDICA CORP. (US) | 2017-04-27 | — | — | WO | disclosed |
| WO-2011034860-A1 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | ICAGEN, INC. (US) | 2011-03-24 | — | — | WO | disclosed |