Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 15/20 | 0.71 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14437487 | 0.83 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1NPC1RAB9A | |
| SCHEMBL12811867 | 0.78 | KCNN4 (0.88) | KCNN4KCNE1KCNQ1NPC1RAB9A | |
| SCHEMBL13427555 | 0.76 | KCNN4 (0.71) | KCNN4KCNE1KCNQ1NPC1RAB9A | |
| SCHEMBL13427600 | 0.71 | KCNN4 (0.63) | KCNN4KCNE1KCNQ1NPC1RAB9A | |
| SCHEMBL5055356 | 0.70 | KCNN4 (0.67) | KCNN4KCNE1KCNQ1NPC1RAB9A | |
| SCHEMBL5052734 | 0.70 | KCNN4 (0.53) | KCNN4KCNE1KCNQ1CYP1A2CYP2C9 | |
| SCHEMBL16191081 | 0.67 | KCNN4 (0.50) | KCNN4NPC1RAB9AVNN1 | |
| SCHEMBL5181410 | 0.64 | KCNN4 (0.44) | KCNN4CYP1A2 | |
| SCHEMBL5180932 | 0.64 | KCNN4 (0.43) | KCNN4NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL13950934 | 0.63 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034860-A1 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | ICAGEN, INC. (US) | 2011-03-24 | — | — | WO | disclosed |