Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12811761 | 1.00 | BRD4 (0.37) | BRD4KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20924944 | 0.98 | BRD4 (0.38) | BRD4KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20924990 | 0.95 | BRD4 (0.41) | BRD4KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL21612456 | 0.81 | BRD4 (0.38) | BRD4KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL21612455 | 0.81 | BRD4 (0.38) | BRD4KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20924858 | 0.80 | BRD4 (0.43) | BRD4KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31310089 | 0.76 | TSHR (0.33) | KMT2AMAPTALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL14902301 | 0.74 | BRD4 (0.35) | BRD4KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15636529 | 0.73 | GAA (0.35) | KMT2AMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL7150874 | 0.71 | ATM (0.40) | KMT2AMAPTALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902034-B1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS SA (CH) | 2011-03-30 | — | — | EP | disclosed |