Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 15/20 | 0.71 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | PRKACA | P17612 | 1/20 | 0.61 |
| ▸ | GSK3A | P49840 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | PRKX | P51817 | 1/20 | 0.61 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420492 | 0.92 | AOC3 (0.71) | AOC3HSD17B2 | |
| SCHEMBL11422442 | 0.90 | AOC3 (0.68) | AOC3HSD17B2 | |
| SCHEMBL11426776 | 0.88 | AOC3 (0.80) | AOC3 | |
| SCHEMBL11419447 | 0.86 | AOC3 (0.74) | AOC3 | |
| SCHEMBL11419343 | 0.86 | AOC3 (0.74) | AOC3 | |
| SCHEMBL11426786 | 0.85 | AOC3 (0.68) | AOC3HSD17B2 | |
| SCHEMBL11421913 | 0.85 | AOC3 (0.68) | AOC3 | |
| SCHEMBL11426964 | 0.84 | AOC3 (0.74) | AOC3 | |
| SCHEMBL11419381 | 0.84 | AOC3 (0.77) | AOC3 | |
| SCHEMBL10317644 | 0.83 | AOC3 (1.00) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |
| US-8802679-B2 | Glycine compound | ASTELLAS PHARMA INC. (JP) | 2014-08-12 | — | — | US | disclosed |
| WO-2011034078-A1 | GLYCINE COMPOUND | アステラス製薬株式会社 (JP) | 2011-03-24 | — | — | WO | disclosed |