Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.59 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.59 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27134479 | 0.87 | RXFP1 (0.67) | MEN1KMT2AALDH1A1L3MBTL1SLC10A2 | |
| SCHEMBL9189162 | 0.84 | MEN1 (0.64) | MEN1KMT2AALDH1A1HSD17B10POLB | |
| SCHEMBL533767 | 0.83 | KCNK3 (0.81) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL9471092 | 0.82 | MEN1 (0.64) | MEN1KMT2AALDH1A1L3MBTL1SLC10A2 | |
| SCHEMBL14396861 | 0.82 | BRAF (0.58) | MEN1KMT2AALDH1A1L3MBTL1SLC10A2 | |
| SCHEMBL259352 | 0.81 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL3356211 | 0.81 | MEN1 (1.00) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL16941525 | 0.81 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL31424193 | 0.81 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL7181742 | 0.81 | MEN1 (0.71) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277738-B1 | CONDENSED HETEROARYL DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2011-03-30 | — | — | EP | disclosed |