Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 14/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733047 | 0.87 | QPCT (0.42) | QPCTQPCTLNPC1KDM4EMAPT | |
| SCHEMBL12812820 | 0.82 | HDAC1 (0.39) | MMP1MMP13KMT2AHDAC1KCNA5 | |
| SCHEMBL1444538 | 0.81 | QPCT (0.56) | QPCTQPCTL | |
| SCHEMBL12733267 | 0.79 | QPCT (0.49) | QPCTQPCTL | |
| SCHEMBL29410457 | 0.78 | QPCT (0.53) | QPCTQPCTL | |
| SCHEMBL1673351 | 0.78 | QPCT (0.53) | QPCTQPCTL | |
| SCHEMBL1444517 | 0.78 | QPCT (0.46) | QPCTQPCTLKMT2A | |
| SCHEMBL12733251 | 0.77 | QPCT (0.47) | QPCTQPCTL | |
| SCHEMBL12813772 | 0.77 | QPCT (0.47) | QPCTQPCTL | |
| SCHEMBL12812822 | 0.76 | QPCT (0.60) | QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029920-A1 | HETEROCYLCIC DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2011-03-17 | — | — | WO | disclosed |