Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 12/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441109 | 0.92 | F9 (0.52) | F9DDB1CRBNALDH1A1KMT2A | |
| SCHEMBL1439372 | 0.91 | F9 (0.51) | F9DDB1CRBNALDH1A1MAPT | |
| SCHEMBL1438640 | 0.91 | F9 (0.50) | F9DDB1CRBNPGR | |
| SCHEMBL1441849 | 0.89 | F9 (0.49) | F9DDB1CRBNALDH1A1 | |
| SCHEMBL12812955 | 0.89 | F9 (0.50) | F9KCNQ2KDM4EALDH1A1KMT2A | |
| SCHEMBL12812956 | 0.89 | F9 (0.54) | F9DDB1CRBNKCNQ2KDM4E | |
| SCHEMBL1438630 | 0.89 | F9 (0.51) | F9KMT2A | |
| SCHEMBL12816537 | 0.88 | F9 (0.53) | F9KMT2AMEN1 | |
| SCHEMBL15108885 | 0.88 | F9 (0.53) | F9KMT2AMEN1 | |
| SCHEMBL12548273 | 0.87 | F9 (0.48) | F9ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025565-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-03-03 | — | — | WO | disclosed |