Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444178 | 0.91 | F9 (0.38) | F9DRD2MEN1ALDH1A1KMT2A | |
| SCHEMBL1444174 | 0.91 | F9 (0.38) | F9DRD2MEN1ALDH1A1KMT2A | |
| SCHEMBL12548136 | 0.89 | F9 (0.47) | F9DRD2MEN1ALDH1A1KMT2A | |
| SCHEMBL1948427 | 0.81 | F9 (0.49) | F9MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL1948293 | 0.81 | F9 (0.47) | F9ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1949460 | 0.81 | F9 (0.60) | F9MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL1949463 | 0.81 | F9 (0.60) | F9MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL1949954 | 0.80 | F9 (0.45) | F9MAPTARKDM4E | |
| SCHEMBL12548187 | 0.80 | F9 (0.38) | F9DRD2MEN1ALDH1A1KMT2A | |
| SCHEMBL1440857 | 0.79 | F9 (0.51) | F9HPGDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025565-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-03-03 | — | — | WO | disclosed |