Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.62 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813060 | 0.94 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R2MAPK8MAPK9 | |
| SCHEMBL12813115 | 0.87 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3R2MAPK8MAPK9 | |
| Trifluoroacetic Acid SCHEMBL12812979 | 0.84 | PIK3CD (0.88) | PIK3CDPIK3CGPIK3R2PIK3CBPIK3R1 | |
| SCHEMBL12813133 | 0.84 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3R2MAPK8MAPK9 | |
| SCHEMBL12813128 | 0.78 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3R1 | |
| SCHEMBL12813098 | 0.77 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3R2MAPK8MAPK9 | |
| Trifluoroacetic Acid SCHEMBL15487455 | 0.77 | PIK3CD (0.75) | PIK3CDPIK3CGPIK3R2PIK3CBPIK3CA | |
| SCHEMBL12813084 | 0.77 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3R2MAPK8MAPK9 | |
| SCHEMBL12813059 | 0.77 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R2PIK3CBPIK3R1 | |
| SCHEMBL12813252 | 0.76 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3R2PIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012135009-A1 | PYRIMIDINE-4,6-DIAMINE DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-10-04 | — | — | WO | disclosed |